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Fig. 1 | BMC Bioinformatics

Fig. 1

From: msPIPE: a pipeline for the analysis and visualization of whole-genome bisulfite sequencing data

Fig. 1

Overview of the msPIPE workflow. Using WGBS read files and UCSC assembly name of a reference as input, the msPIPE automates the entire DNA methylation analysis starting from input data pre-processing to methylation analysis. The reference genome sequences and annotation files of input species are collected from the UCSC genome browser. The trimmed reads are mapped to the bisulfite-converted genome sequences, and methylation calls are made. Based on these methylation calls, methylation profiling, hypomethylated regions analysis, differential methylation analysis, and the function analysis for methylation-related genes are performed

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