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Table 2 Comparison among APA-Scan, DaPars and APAtrap on simulated RNA-seq data with two different sequencing depths (30 million reads and 50 million reads)

From: APA-Scan: detection and visualization of 3′-UTR alternative polyadenylation with RNA-seq and 3′-end-seq data

Reads

Method

AUC

Sensitivity

Specificity

30 M

APA-Scan

0.94

0.83

0.95

DaPars

0.65

0.33

0.58

APAtrap

0.73

0.57

0.90

50 M

APA-Scan

0.94

0.83

0.95

DaPars

0.68

0.41

0.71

APAtrap

0.75

0.63

0.91

  1. AUC (the area under the ROC curve) score, sensitivity, specificity of the three methods are reported. The best results across the three methods are bold