Fig. 6

The role of collagen VI family in colorectal cancer. A–B COL6A gene expression levels in C1-C6 immune subtype in COAD and READ, respectively. C1, wound healing; C2, IFN-γ dominant; C3, inflammatory; C4, lymphocyte depleted; C5, immunologically quiet; C6, TGF-β dominant. *p < 0.05; **p < 0.01; ***p < 0.001. C–D The correlation between COL6A gene expression and RNAss, DNAss, stromal scores, immune score, and estimate scores in COAD and READ, respectively. R means correlation coefficient. P represents statistical significance. RNAss: RNA-based stemness scores; DNAss: DNA methylation-based stemness scores; COAD: Colon adenocarcinoma; READ: Rectum adenocarcinoma