Table 3 Results of ablation experiments
From: Deep learning and multi-omics approach to predict drug responses in cancer
Omics combination | MSE | \(\mathrm {R^2}\) |
|---|---|---|
mut-rppa | 0.26 ± 0.01 | 0.91 ± 0.01 |
exp-mut-rppa | 0.27 ± 0.01 | 0.90 ± 0.01 |
exp-mut | 0.27 ± 0.01 | 0.90 ± 0.01 |
mut-cnv-rppa | 0.28 ± 0.01 | 0.90 ± 0.01 |
exp-mut-cnv-rppa | 0.28 ± 0.01 | 0.90 ± 0.01 |
mut-rppa-metabolites | 0.28 ± 0.01 | 0.90 ± 0.01 |
mut-cnv | 0.28 ± 0.01 | 0.90 ± 0.01 |
exp-mut-rppa-metabolites | 0.28 ± 0.01 | 0.90 ± 0.01 |
exp-mut-cnv | 0.28 ± 0.01 | 0.90 ± 0.01 |
exp-mut-metabolites | 0.28 ± 0.01 | 0.90 ± 0.01 |
exp-mut-cnv-rppa-metabolites | 0.28 ± 0.01 | 0.90 ± 0.01 |
mut-metabolites | 0.28 ± 0.01 | 0.90 ± 0.01 |
mut-cnv-rppa-metabolites | 0.28 ± 0.01 | 0.90 ± 0.01 |
exp-mut-cnv-metabolites | 0.28 ± 0.01 | 0.90 ± 0.01 |
mut-cnv-metabolites | 0.28 ± 0.01 | 0.90 ± 0.01 |
exp-rppa | 0.66 ± 0.04 | 0.78 ± 0.02 |
exp-cnv-rppa | 0.67 ± 0.04 | 0.78 ± 0.02 |
cnv-rppa | 0.67 ± 0.04 | 0.78 ± 0.02 |
exp-rppa-metabolites | 0.67 ± 0.04 | 0.78 ± 0.02 |
exp-cnv-rppa-metabolites | 0.67 ± 0.04 | 0.78 ± 0.02 |
rppa-metabolites | 0.67 ± 0.04 | 0.78 ± 0.02 |
cnv-rppa-metabolites | 0.67 ± 0.04 | 0.78 ± 0.02 |
exp-cnv | 1.08 ± 0.05 | 0.65 ± 0.02 |
exp-cnv-metabolites | 1.08 ± 0.05 | 0.65 ± 0.02 |
exp-metabolites | 1.08 ± 0.05 | 0.65 ± 0.02 |
cnv-metabolites | 1.84 ± 0.05 | 0.44 ± 0.03 |