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Fig. 3 | BMC Bioinformatics

Fig. 3

From: Estimating the effect size of a hidden causal factor between SNPs and a continuous trait: a mediation model approach

Fig. 3

Results of one simulation setting: base case, varying bH, 1000 simulations. The first and second row presents the results for 70 SNPs and 500 SNPs, respectively. (A, E) Box plots of the posterior median and the mean of bH. The purple lines indicate the true values. (B, F) Box plots of the widths of 90% HDIs and QIs. (C, G) The posterior medians and the 90% HDIs of the 49 equally spaced values of bH between 0.02 and 0.5. (D, H) The posterior means and the 90% QIs of the 49 equally spaced values of bH between 0.02 and 0.5. Outliers are defined as the values more extreme than the third quartile + 1.5 * (the third quartile—the first quartile) or the first quartile—1.5 * (the third quartile—the first quartile)

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