Table 2 MDPA is compared with FPOCKET and CAVIAR for the prediction of binding pockets of the structures in the CCDC/Astex dataset
From: A multilayer dynamic perturbation analysis method for predicting ligand–protein interactions
Method | Ligand-binding Site Prediction | Ligand overlap | ||
|---|---|---|---|---|
percentage with precision > 30% | percentage with recall > 30% | percentage with precision > 30% | percentage with recall > 30% | |
MDPA | 60% | 80% | 71% | 78% |
FPOCKET | 56% | 85% | 65% | 81% |
CAVIAR | – | – | 70% | 89% |