Skip to main content

Table 1 Results of identifying protein biomarkers

From: Automated classification of protein expression levels in immunohistochemistry images to improve the detection of cancer biomarkers

Protein

Predicted expression level change

Expression level change (P value)

Subcellular location change (P value)

BCAR1

Medium → Low

0.5437

Nucl.: 0.0455

ELAVL1

Medium → High

0.7435

Cytopl.: 3.6e-5

NDRG1

High → Medium

3.37e-4

PlasMem.: 0.1675

Nucl.: 0.1005

CCNEL

Medium → Low

0.0706

Nucl.: 0.8563

AHR

Medium → Low

0.0094

Nucl.: 0.0158

p68

Medium → Low

0.0029

Cytopl.: 4.6e-7

EBP50

High → Medium

0.1086

Nucl.: 0.0076

CDKN1B

Medium → Low

2.14e-3

Cytopl.: 6.65e-8

CACYBP

Medium → High

2.85e-7

Nucl.: 1.03e-5

ARRB1

High → Low

0.5986

PlasMem.: 1.12e-3

p53

High → Medium

9.34e-3

Cytopl.: 0.0498

Nucl.: 0.0365

BRD4

High → Low

0.0376

Nucl.: 1.3e-5

AKT1

Medium → Low

1.04e-3

Cytopl.: 0.0204

PRKCA

Medium → Low

2.13e-3

PlasMem.: 4.04e-11

SMAD3

Medium → Low

0.0225

Nucl.: 0.0249

HNRNPK

High → Low

0.1058

Cytopl.: 3.46e-4

Nucl.: 0.0110

PRKCB

Low → High

0.3276

PlasMem.: 0.0240

ß-catenin

Medium → Low

0.6826

Cytopl.:1.65e-4

Nucl.: 2.86e-4

STAT3

Medium → Low

5.88e-4

Nucl.: 5.2e-5

TET2

Medium → High

0.0491

Cytopl.:1.86e-3

BCL2

Low → Medium

0.0203

Nucl.: 0.2644

PlasMem.: 0.1820

CYSLT1

Low → Medium

0.0178

Nucl.: 0.5582

  1. The bold are the screened cancer biomarkers