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Table 4 Genes Selected by Grace-AKO in the application of prostate cancer and PSA pathways

From: Grace-AKO: a novel and stable knockoff filter for variable selection incorporating gene network structures

Genes name

CHR

Genes Expression

ANAPC7

12

Ubiquitous expression in testis (RPKM 11.7), esophagus (RPKM 9.0) and 25 other tissues

AK6

5

Ubiquitous expression in testis (RPKM 18.6), adrenal (RPKM 17.2) and 25 other tissues

CHRNB2

1

Biased expression in brain (RPKM 9.5), adrenal (RPKM 0.7) and 1 other tissue

COL4A5

X

Broad expression in endometrium (RPKM 21.7), skin (RPKM 10.8) and 20 other tissues

PRLR

5

Biased expression in placenta (RPKM 18.9), endometrium (RPKM 11.6) and 8 other tissues

CAMK4

5

Broad expression in brain (RPKM 7.0), lymph node (RPKM 3.7) and 21 other tissues

CHRNB2

1

Biased expression in brain (RPKM 9.5), adrenal (RPKM 0.7) and 1 other tissue

PPP2R2D

10

Ubiquitous expression in pancreas (RPKM 6.3), ovary (RPKM 5.9) and 25 other tissues

IFNA13

9

–

COL1A1

17

Biased expression in gall bladder (RPKM 850.7), urinary bladder (RPKM 497.1) and 11 other tissues

RBPJ

4

Ubiquitous expression in placenta (RPKM 17.3), endometrium (RPKM 16.0) and 25 other tissues

PARD6G

18

Broad expression in skin (RPKM 15.6), esophagus (RPKM 5.7) and 15 other tissues

ZNF766

19

Ubiquitous expression in testis (RPKM 7.0), thyroid (RPKM 4.6) and 25 other tissues

PRKACG

9

–

SPDYE4

17

Restricted expression toward testis (RPKM 1.5)

PRKACA

19

Ubiquitous expression in heart (RPKM 62.0), adrenal (RPKM 43.9) and 25 other tissues

HLA-DRB5

6

Broad expression in lung (RPKM 275.5), lymph node (RPKM 163.3) and 14 other tissues

ZNF671

19

Ubiquitous expression in spleen (RPKM 4.7), lymph node (RPKM 4.6) and 25 other tissues

ZNF492

19

Broad expression in testis (RPKM 1.4), bone marrow (RPKM 0.9) and 16 other tissues

MAPK3

16

Ubiquitous expression in small intestine (RPKM 45.8), colon (RPKM 42.8) and 25 other tissues

ZNF461

19

Ubiquitous expression in testis (RPKM 1.8), thyroid (RPKM 1.6) and 25 other tissues

CCNE1

19

Biased expression in placenta (RPKM 16.5), bone marrow (RPKM 11.3) and 12 other tissues

CCR3

3

–

ZNF251

8

Ubiquitous expression in endometrium (RPKM 6.9), thyroid (RPKM 6.8) and 25 other tissues

CSH1

17

Restricted expression toward placenta (RPKM 9553.7)

ACTG1

17

Ubiquitous expression in ovary (RPKM 1227.2), esophagus (RPKM 970.4) and 25 other tissues

TH

11

Restricted expression toward adrenal (RPKM 42.8)

ANF853

–

–

CDC27

17

Ubiquitous expression in thyroid (RPKM 20.3), testis (RPKM 11.6) and 25 other tissues

H2AC14

6

–

H2AC7

6

–

IL9

5

–

IL5RA

3

Biased expression in lung (RPKM 1.2), prostate (RPKM 0.7) and 13 other tissues

IFNA7

9

–

IFNA2

9

–

FARR2

-

–

ZNF248

10

Ubiquitous expression in endometrium (RPKM 2.8), thyroid (RPKM 2.7) and 24 other tissues

IFNA17

9

–

ZNF331

19

Broad expression in adrenal (RPKM 22.0), placenta (RPKM 9.5) and 20 other tissues

ZNF473

19

Broad expression in testis (RPKM 14.8), spleen (RPKM 2.3) and 21 other tissues

ZNF713

7

Broad expression in brain (RPKM 2.1), testis (RPKM 1.9) and 25 other tissues

COL9A1

6

Biased expression in prostate (RPKM 6.1), testis (RPKM 1.3) and 6 other tissues

H2BC9

6

–

PDGFB

22

Broad expression in placenta (RPKM 18.6), fat (RPKM 12.7) and 23 other tissues

MYC

8

Ubiquitous expression in gall bladder (RPKM 49.6), esophagus (RPKM 44.6) and 25 other tissues

  1. CHR stands for chromosome