Fig. 2
From: Modeling and cleaning RNA-seq data significantly improve detection of differentially expressed genes
Distribution of mRNAs counts in polysomal and monosomal mRNA fractions. Figures show the number of genes with respective mRNA count for raw mRNA data (red line), cleaned data (blue) and exponentially distributed counts (black). Subtraction values x are calculated independently for each sample (repetition and fraction), and are defined as a 0.99 quantile of the respective exponential distribution. Distribution of cleaned data (blue line) is now very close to negative binomial