Fig. 5

Performance comparison of GRN reconstruction for different in-silico networks modeled from E. coli & Yeast. x-axis shows different combinations of [MI estimator, inference algo], y-axis shows percentage AUPR difference (increase or decrease) relative to the gold standard combination [ML,CLR]. A Sorted boxplots of the combined four E. coli networks from DREAM3. Each boxplot represents 40 networks (4 different networks X 10 replicates). B same as (A) but for the six Yeast networks. C–F Sorted boxplots of the 4 different E. coli networks from DREAM3. Each boxplot represents 10 replicates. Green bar inside each boxplot represents median AUPR value. A complete list of tested MI estimators & GRN inference algo can be found in Additional file 2: Table S2