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Fig. 5 | BMC Bioinformatics

Fig. 5

From: Early effects of gene duplication on the robustness and phenotypic variability of gene regulatory networks

Fig. 5

Access to new phenotypes through mutation before and after adding a duplicate gene. a New phenotypes accessible through mutation before and after gene duplication. The circle on the left represents the set of phenotypes that a GRN can access before duplication. The one on the right represents the same set but after gene duplication. The green area represents lost accessible phenotypes, only accessible before duplication. The orange area represents newcomer accessible phenotypes that only become accessible after duplication. The intersection, in blue, represents recurrently accessible phenotypes, accessible both before and after gene duplication. b The number of distinct accessible phenotypes before and after duplication in all, duplication-resistant and duplication susceptible GRNs. c Average number of mutations that lead to each lost and recurrently accessible phenotype. d Average similarity of accessible phenotypes to the original phenotype A

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BMC Bioinformatics

ISSN: 1471-2105

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