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Fig. 4 | BMC Bioinformatics

Fig. 4

From: iDMET: network-based approach for integrating differential analysis of cancer metabolomics

Fig. 4

Differential metabolomic network based on the published cancer metabolomic datasets. Metabolomic data from the list of papers in Table 1 were used to generate the network in (A). Each node represents a comparison of a metabolomic profile pair (differential metabolomic profile). A pair of nodes are connected by an edge if the corresponding pair of differential metabolomic profiles are correlated (see also Fig. 2). The node color reflects the source article, where the same color denotes that the corresponding source data are from the same paper. The widths of edges indicate odds ratio weights. The node size depicts the total number of differential metabolites for each dataset. The network connects metabolomic data not only from the same laboratory (denoted by dotted edges), but also those from different laboratories (denoted by solid edges). The subnetwork of (a) that contains a strong connection between P17-1 and P24-1 is magnified in (b) and further assessed in Fig. 5. The network was visualized by Cytoscape

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