Fig. 4

Estimated proportion of the minor variant in synthetic mixtures of the Delta and Omicron variants. Blue crosses represent the true proportion of the minor variant. Orange lines represent the median, red circles are outliers. In each setting, the graphs show the distribution for 20 randomly generated data sets with the prescribed minor variant proportion, with Delta and Omicron playing the role of the minor variant in 10 samples each. The average coverage for each synthetic data set was 5000