Table 4 Top 10 performing quantification tool combinations at the lowest computational cost in the simulated dataset, ranked by F1 score
Combination | Precision (%) | Sensitivity (%) | F1 (%) |
|---|---|---|---|
CIRCexplorer2,CIRIquant,Segemehl | 98.47 | 97.21 | 97.83 |
CIRIquant,MapSplice,Segemehl | 98.55 | 96.99 | 97.76 |
CIRCexplorer2,CIRIquant,find_circ | 99.59 | 95.89 | 97.70 |
CIRCexplorer2,CIRIquant,MapSplice | 99.74 | 95.54 | 97.60 |
CIRIquant,find_circ,MapSplice | 99.70 | 95.57 | 97.59 |
CIRCexplorer2,find_circ,Segemehl | 98.33 | 96.57 | 97.45 |
CIRCexplorer2,MapSplice,Segemehl | 98.50 | 96.41 | 97.44 |
CIRIquant,find_circ,Segemehl | 98.37 | 96.46 | 97.41 |
CIRCexplorer2,find_circ,MapSplice | 99.61 | 95.28 | 97.40 |
CIRCexplorer2,CIRIquant,circRNA_finder | 97.51 | 97.18 | 97.35 |