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Fig. 2 | BMC Bioinformatics

Fig. 2

From: GBCdb: RNA expression landscapes and ncRNA–mRNA interactions in gallbladder carcinoma

Fig. 2

RNA interaction network. A A volcano plot shows the differentially expressed miRNAs identified from GSE104165. B The distribution of AveExpr of the screened differentially expressed miRNAs from A. C Distribution of expressions of homologous miRNAs in the let-7 gene family in tumor samples. The red dotted line indicates the median value of the total expression levels. D The miRNA-mRNA interaction network of the differentially expressed RNAs (at least in one dataset). A specific network is presented with multiple interactions for some miRNAs and mRNAs. The detailed distributions of frequencies are also presented. E An example of mRNA-miRNA-lncRNA network; each RNA is significantly up-regulated or down-regulated in tumor samples. F Examples of several mRNAs, miRNAs and lncRNAs that are significantly dysregulated in GBC. *Indicates |log2FC|> 1.2 and padj < 0.05

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