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Table 9 AUROC and AP for simulated dataset with confounding covariates

From: LuxHMM: DNA methylation analysis with genome segmentation via hidden Markov model

Method

AUROC

AP

LuxHMM \(^{1}\)

0.823

0.536

LuxHMM \(^{2}\)

0.756

0.549

LuxUS

0.679

0.321

RADMeth

0.644

0.246

metilene

0.714

0.348

HMM-DM

0.616

0.180

DMRcate

0.658

0.065

DSS

0.672

0.339

  1. Bold represent the highest values in each column
  2. 1 All regions
  3. 2 Hypo- and hypermethylated regions