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Fig. 2 | BMC Bioinformatics

Fig. 2

From: Immunoinformatics-aided design of a new multi-epitope vaccine adjuvanted with domain 4 of pneumolysin against Streptococcus pneumoniae strains

Fig. 2

The amino acid sequence, schematic diagram, and 3D refined structure of the vaccine candidate. A The final protein sequence of the multi-epitope construct consisted of 590 residues. The linkers EAAAK and GPGPG are shown in cyan and yellow, respectively. B The schematic image of vaccine construct was obtained from the selected regions of Ply4, PhtD and PspA, as well as linkers EAAAK and GPGPG, which are shown in red, purple, magenta, cyan and yellow, respectively. C The refined model was provided by the GalaxyRefine server and visualized by the Discovery Studio Visualizer. The regions of Ply4, PhtD and PspA are shown in red, purple, and magenta, respectively

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