PriPath: identifying dysregulated pathways from differential gene expression via grouping, scoring, and modeling with an embedded feature selection approach

Table 2 An example of KEGG groups with their associated genes

KEGG pathway ID	Group name	Genes	References
hsa05220	Chronic myeloid leukemia	TP53, MYC, HRAS, KRAS, …	[29]
hsa00670	One carbon pool by folate	MTHFD2, DHFR, DHFR2, MTHFD1L, …	[30]
hsa05033	Nicotine addiction	GABRA5, CACNA1B, GABRE, GABRD, …	[31]
hsa05200	Cancer	GNG4, CTNNA1, TP53, MYC, …	[32]
hsa05216	Thyroid cancer	TP53, MYC, TCF7L1, MAPK1, …	[33]
hsa04723	Retrograde endocannabinoid signaling	GNG4, MAPK9, PRKCG, GABRA5,…	[34]

The first column is the KEGG pathway ID, the second column refers to the KEGG pathway name (group name), and the third column is the set of genes associated with the KEGG pathway

ISSN: 1471-2105