Fig. 3

Cell-to-cell variability analysis of human renal macrophages. Comparison of transcriptional divergence across species with cell-to-cell variability between individual cellswhere the variability were measured in A n = 318 resident macrophages (high vs low, one-sided Mann‒Whitney test, P-value < 0.01) and B n = 143 infiltrated macrophages (high vs low, one-sided Mann‒Whitney test, P-value < 0.01) in human kidney. Comparison of cell-to-cell variability of genes with and without a TATA-box in C resident macrophages (one-sided Mann‒Whitney test, P-value < 0.01) and D infiltrated macrophages (one-sided Mann‒Whitney test, P-value < 0.01). E Comparison of cell-to-cell variability of genes with and without a CGI in resident macrophages (one-sided Mann‒Whitney test, P-value = 0.0179)