Fig. 2

Prognostic risk score model construction. A Forest plot of 17 bacterial response-related DEGs associated with prognosis. B The mutation frequency of the 17 bacterial response-related DEGs in 447 CC patients from TCGA. C Mutational co-occurrence (green) and exclusion (purple) analyses of the 17 bacterial response-related DEGs. D LASSO coefficients of the seven bacterial response-related DEGs. E Construction of the prognostic risk score model. F PCA of all bacterial response-related genes in the training set. G PCA of the bacterial response risk score to separate CC samples from normal samples in the training set; red indicates patients with a high risk score, and blue indicates patients with a low risk score. H and I OS of training and test sets in the two risk score groups. J Progression-free survival of the training set in the two risk score groups. K Relapse-free survival of the test set in the two risk score groups. L ROC curves of the predictive efficiency in the training set. M and N Forest plots of univariate and multivariate Cox regression analyses in the training set