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Fig. 2 | BMC Bioinformatics

Fig. 2

From: multiWGCNA: an R package for deep mining gene co-expression networks in multi-trait expression data

Fig. 2

multiWGCNA reveals an EAE-specific network in astrocytes. (a) Preservation scores of modules from EAE network in wildtype network, using astrocyte Ribotag data. (b) Distribution of expected preservation scores for modules of similar size to dM15 when phenotype labels are randomly assigned (2000 permutations). (c) Network view of the correspondence (based on hypergeometric overlap p value) between dM15 and the other modules constructed by multiWGCNA. (d) Expression patterns of the top 20 connected genes in dM15, showing highly unsynchronized expression in the wildtype samples

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