Fig. 1From: Priors, population sizes, and power in genome-wide hypothesis testsGWAS progress for breast cancer susceptibility cohorts and loci. Manhattan plots depict GWAS findings for breast cancer as of 2010 (top panel), 2015 (middle panel), and 2020 (bottom panel). In each panel, the x-axis represents genomic coordinates to scale, and the y-axis is the \(-\log _{10}\) p value for a GWAS association with a SNP; a dashed line indicates the genome-wide significance threshold, \(p = 5\times 10^{-8}\). The SNP color alternates blue/green by chromosome, with lighter colors for findings below threshold and saturated colors above thresholdBack to article page