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Fig. 10 | BMC Bioinformatics

Fig. 10

From: Priors, population sizes, and power in genome-wide hypothesis tests

Fig. 10

Non-oracular priors for RNAseq. Same as Fig. 9, but for RNAseq, with significance \(p = 2\times 10^{-6}\) typically requested. Equal performance (solid line) of a non-oracular prior and of no prior is defined by the \(R^2\) that can be detected with 50% power (left), 80% power (middle), or 95% power (right) at \(p = 5\times 10^{-8}\). Performance is depicted for non-oracular priors having accuracy f from 0% to 100% (equivalent to an oracular prior) and having prior strength S from 1 to 1000. Accuracies for equal performance at prior strength 10, 100, and 1000 are shown (labeled points). Above the line, the non-oracular prior performs better; below the line, the non-oracular prior performs worse and should be avoided

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