Fig. 1
From: Improving variant calling using population data and deep learning
The population-aware DeepVariant (DeepVariant-AF) model. Dashed blue lines represent the typical population-agnostic DeepVariant approach, and the green lines show the data flow of the population-aware method. The green box shows the allele-matching algorithm to match variant alleles with a reference panel. This algorithm first queries cohort variants overlapped with the variant candidate and determines the window where haplotypes are updated. It then compares the haplotypes and updates the allele frequency of the matched ones