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Table 1 Current entry points of CAGECAT and their inputs and outputs

From: CAGECAT: The CompArative GEne Cluster Analysis Toolbox for rapid search and visualisation of homologous gene clusters

Tool

Purpose

Input

Output

Cblaster

(Search module)

Search homologous gene clusters

FASTA (protein)

GenBank

NCBI accessions

HMM profile identifiers

Interactive hit visualisation (HTML)

Summary table

Session file (JSON)

Clinker

(Visualisation module)

Visualise genomes containing homologous gene clusters (all vs. all)

GenBank

Interactive cluster visualisation (HTML)

Recompute

Re-filter a previous search with new parameters

Session file output of cblaster search (JSON format)

Interactive hit visualisation (HTML)

Summary table

Session file (JSON)

Extract sequences

Extract sequences which contain a certain query

Protein sequences (FASTA)

Protein headers (TXT)

Extract clusters

Extract selected clusters

GenBank

Gene Neighborhood Estimation (GNE)

Check intergenic gap from results to optimize parameter

Summary file (TXT)—Interactive visualisation (HTML)

Plot clusters

Visualise a search session (align queries to clusters)

Interactive visualisation (HTML)

  1. cblaster enables gene cluster searches and clinker creates publication-ready gene cluster visualisations. Additional downstream functions can be executed directly form results of previous session