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Fig. 9 | BMC Bioinformatics

Fig. 9

From: Reducing Boolean networks with backward equivalence

Fig. 9

Excerpt of the BN from [30]. It refers to the receptor TLR5 and its signalling to the four following genes: TICAM1, MyD88, IRAK4, PIK3AP1. When a virus infects an organism, the receptor TLR5 receives the relevant antigen stimuli becoming active (the value of \(x_{TLR5}\) turns from 0 to 1), and the signal is subsequently propagated to the other connected genes. (Top) The update functions of the BN. (Bottom-left) Variables are commonly depicted as nodes in a network while directed links represent influences between them. A directed link from a source variable to a target variable denotes that the source variable exists in the update function of the target variable. (Bottom-right) The corresponding STG, where we use purple to denote attractors

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