gene | MOVA | PolyPhen-2 | CADD | REVEL | EVE | AlphScore |
---|---|---|---|---|---|---|
TARDBP | 0.772 | 0.583 | 0.555 | 0.742 | 0.571 | 0.448 |
FUS | 0.841 | 0.541 | 0.694 | 0.878 | – | 0.652 |
SETX | 0.678 | 0.692 | 0.675 | 0.682 | 0.649 | 0.577 |
TBK1 | 0.513 | 0.721 | 0.748 | 0.785 | – | 0.603 |
OPTN | 0.501 | 0.686 | 0.693 | 0.804 | 0.72 | 0.589 |
SOD1 | 0.786 | 0.774 | 0.737 | 0.805 | 0.8 | 0.771 |
VCP | 0.847 | 0.753 | 0.692 | 0.759 | 0.403 | 0.654 |
SQSTM1 | 0.473 | 0.661 | 0.541 | 0.775 | 0.504 | 0.548 |
ANG | 0.464 | 0.593 | 0.555 | 0.721 | 0.554 | 0.443 |
UBQLN2 | 0.769 | 0.47 | 0.464 | 0.722 | 0.562 | 0.527 |
DCTN1 | 0.524 | 0.558 | 0.577 | 0.617 | 0.709 | 0.553 |
CCNF | 0.696 | 0.533 | 0.615 | 0.581 | 0.619 | 0.578 |
Average | 0.655 | 0.63 | 0.629 | 0.739 | 0.609 | 0.579 |