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Imaging, image analysis and data visualization

Section edited by Hanchuan Peng

This section incorporates all aspects of imaging and bioimage informatics, including but not limited to: microscopic and biomedical image acquisition methods and applications, methods and applications of image analysis and related machine learning, pattern recognition and data mining techniques, image oriented multidimensional data and metadata visualization techniques, methods and applications of bioimage annotation and ontology generation.

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  1. Content type: Software

    Drosophila melanogaster is an important organism used in many fields of biological research such as genetics and developmental biology. Drosophila wings have been widely used to study ...

    Authors: Sheng Yang Michael Loh, Yoshitaka Ogawa, Sara Kawana, Koichiro Tamura and Hwee Kuan Lee

    Citation: BMC Bioinformatics 2017 18:319

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  2. Content type: Software

    Image segmentation and registration techniques have enabled biologists to place large amounts of volume data from fluorescence microscopy, morphed three-dimensionally, onto a common spatial frame. Existing too...

    Authors: Yong Wan, Hideo Otsuna, Holly A. Holman, Brig Bagley, Masayoshi Ito, A. Kelsey Lewis, Mary Colasanto, Gabrielle Kardon, Kei Ito and Charles Hansen

    Citation: BMC Bioinformatics 2017 18:280

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  3. Content type: Methodology Article

    Histopathology image analysis is a gold standard for cancer recognition and diagnosis. Automatic analysis of histopathology images can help pathologists diagnose tumor and cancer subtypes, alleviating the work...

    Authors: Yan Xu, Zhipeng Jia, Liang-Bo Wang, Yuqing Ai, Fang Zhang, Maode Lai and Eric I-Chao Chang

    Citation: BMC Bioinformatics 2017 18:281

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  4. Content type: Software

    Spectral imaging with polarity-sensitive fluorescent probes enables the quantification of cell and model membrane physical properties, including local hydration, fluidity, and lateral lipid packing, usually ch...

    Authors: Miles Aron, Richard Browning, Dario Carugo, Erdinc Sezgin, Jorge Bernardino de la Serna, Christian Eggeling and Eleanor Stride

    Citation: BMC Bioinformatics 2017 18:254

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  5. Content type: Research Article

    Image registration is an important research topic in the field of image processing. Applying image registration to vascular image allows multiple images to be strengthened and fused, which has practical value ...

    Authors: Li Chen, Yuxi Lian, Yi Guo, Yuanyuan Wang, Thomas S. Hatsukami, Kristi Pimentel, Niranjan Balu and Chun Yuan

    Citation: BMC Bioinformatics 2017 18:229

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  6. Content type: Methodology article

    Understanding the working mechanism of the brain is one of the grandest challenges for modern science. Toward this end, the BigNeuron project was launched to gather a worldwide community to establish a big dat...

    Authors: Zhijiang Wan, Yishan He, Ming Hao, Jian Yang and Ning Zhong

    Citation: BMC Bioinformatics 2017 18:197

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  7. Content type: Research article

    In recent years, the microscopy technology for imaging cells has developed greatly and rapidly. The accompanying requirements for automatic segmentation and quantification of the imaged cells are becoming more...

    Authors: Zhenzhou Wang and Haixing Li

    Citation: BMC Bioinformatics 2017 18:189

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  8. Content type: Research Article

    Manual assessment and evaluation of fluorescent micrograph cell experiments is time-consuming and tedious. Automated segmentation pipelines can ensure efficient and reproducible evaluation and analysis with co...

    Authors: Veit Wiesmann, Matthias Bergler, Ralf Palmisano, Martin Prinzen, Daniela Franz and Thomas Wittenberg

    Citation: BMC Bioinformatics 2017 18:176

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  9. Content type: Research article

    Cell image segmentation (CIS) is an essential part of quantitative imaging of biological cells. Designing a performance measure and conducting significance testing are critical for evaluating and comparing the...

    Authors: Jin Chu Wu, Michael Halter, Raghu N. Kacker, John T. Elliott and Anne L. Plant

    Citation: BMC Bioinformatics 2017 18:168

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  10. Content type: Software

    In the evaluation of Stereo-Electroencephalography (SEEG) signals, the physicist’s workflow involves several operations, including determining the position of individual electrode contacts in terms of both rel...

    Authors: Massimo Narizzano, Gabriele Arnulfo, Serena Ricci, Benedetta Toselli, Martin Tisdall, Andrea Canessa, Marco Massimo Fato and Francesco Cardinale

    Citation: BMC Bioinformatics 2017 18:124

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  11. Content type: Research Article

    With rapid advances in genome sequencing and editing technologies, systematic and quantitative analysis of animal behavior is expected to be another key to facilitating data-driven behavioral genetics. The nem...

    Authors: Tsukasa Fukunaga and Wataru Iwasaki

    Citation: BMC Bioinformatics 2017 18:46

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  12. Content type: Research Article

    Visualizing data by dimensionality reduction is an important strategy in Bioinformatics, which could help to discover hidden data properties and detect data quality issues, e.g. data noise, inappropriately lab...

    Authors: Jiaoyun Yang, Haipeng Wang, Huitong Ding, Ning An and Gil Alterovitz

    Citation: BMC Bioinformatics 2017 18:47

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  13. Content type: Research Article

    Bioimage classification is a fundamental problem for many important biological studies that require accurate cell phenotype recognition, subcellular localization, and histopathological classification. In this ...

    Authors: Yang Song, Weidong Cai, Heng Huang, Dagan Feng, Yue Wang and Mei Chen

    Citation: BMC Bioinformatics 2016 17:465

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  14. Content type: Research Article

    New bioimaging techniques capable of visualising the co-location of numerous proteins within individual cells have been proposed to study tumour heterogeneity of neighbouring cells within the same tissue speci...

    Authors: Violeta N. Kovacheva and Nasir M. Rajpoot

    Citation: BMC Bioinformatics 2016 17:430

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  15. Content type: Research article

    Cryo-electron tomography is an important tool to study structures of macromolecular complexes in close to native states. A whole cell cryo electron tomogram contains structural information of all its macromole...

    Authors: Long Pei, Min Xu, Zachary Frazier and Frank Alber

    Citation: BMC Bioinformatics 2016 17:405

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2016 Journal Metrics

  • Citation Impact
    2.448 - 2-year Impact Factor
    3.450 - 5-year Impact Factor
    0.946 - Source Normalized Impact per Paper (SNIP)
    1.467 - SCImago Journal Rank (SJR)

    Usage 
    3784657 downloads
    1405 Usage Factor


    Social Media Impact
    816 mentions

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