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Volume 9 Supplement 1

Asia Pacific Bioinformatics Network (APBioNet) Sixth International Conference on Bioinformatics (InCoB2007)

Proceedings

Edited by Shoba Ranganathan, Michael Gribskov and Tin Wee Tan

Sixth International Conference on Bioinformatics (InCoB2007). Go to conference site.

Hong Kong27-30 August 2007

  1. We provide a 2007 update on the bioinformatics research in the Asia-Pacific from the Asia Pacific Bioinformatics Network (APBioNet), Asia's oldest bioinformatics organisation set up in 1998. From 2002, APBioNe...

    Authors: Shoba Ranganathan, Michael Gribskov and Tin Wee Tan
    Citation: BMC Bioinformatics 2008 9(Suppl 1):S1
  2. Analysis of single nucleotide polymorphism (SNP) is becoming a key research in genomics fields. Many functional analyses of SNPs have been carried out for coding regions and splicing sites that can alter prote...

    Authors: Byoung-Chul Kim, Woo-Yeon Kim, Daeui Park, Won-Hyong Chung, Kwang-sik Shin and Jong Bhak
    Citation: BMC Bioinformatics 2008 9(Suppl 1):S2
  3. Experimentally verified protein-protein interactions (PPI) cannot be easily retrieved by researchers unless they are stored in PPI databases. The curation of such databases can be made faster by ranking newly-...

    Authors: Richard Tzong-Han Tsai, Hsi-Chuan Hung, Hong-Jie Dai, Yi-Wen Lin and Wen-Lian Hsu
    Citation: BMC Bioinformatics 2008 9(Suppl 1):S3
  4. Prediction of transmembrane (TM) helices by statistical methods suffers from lack of sufficient training data. Current best methods use hundreds or even thousands of free parameters in their models which are t...

    Authors: Madhavi Ganapathiraju, N Balakrishnan, Raj Reddy and Judith Klein-Seetharaman
    Citation: BMC Bioinformatics 2008 9(Suppl 1):S4
  5. The indexing of scientific literature and content is a relevant and contemporary requirement within life science information systems. Navigating information available in legacy formats continues to be a challe...

    Authors: Christopher JO Baker, Rajaraman Kanagasabai, Wee Tiong Ang, Anitha Veeramani, Hong-Sang Low and Markus R Wenk
    Citation: BMC Bioinformatics 2008 9(Suppl 1):S5
  6. The most renowned biological ontology, Gene Ontology (GO) is widely used for annotations of genes and gene products of different organisms. However, there are shortcomings in the Resource Description Framework...

    Authors: Qingwei Xu, Yixiang Shi, Qiang Lu, Guoqing Zhang, Qingming Luo and Yixue Li
    Citation: BMC Bioinformatics 2008 9(Suppl 1):S6
  7. Nucleic acid hybridization, a fundamental technique in molecular biology, can be modified into very effective and sensitive methods for detecting particular targets mixed with millions of non-target sequences....

    Authors: Shu-Hwa Chen, Chen-Zen Lo, Ming-Chi Tsai, Chao A Hsiung and Chung-Yen Lin
    Citation: BMC Bioinformatics 2008 9(Suppl 1):S8
  8. Identification of differentially expressed genes is a typical objective when analyzing gene expression data. Recently, Bayesian hierarchical models have become increasingly popular to solve this type of proble...

    Authors: Hongya Zhao, Kwok-Leung Chan, Lee-Ming Cheng and Hong Yan
    Citation: BMC Bioinformatics 2008 9(Suppl 1):S9
  9. The analysis of expressed sequence tags (EST) offers a rapid and cost effective approach to elucidate the transcriptome of an organism, but requires several computational methods for assembly and annotation. R...

    Authors: Shivashankar H Nagaraj, Robin B Gasser, Alasdair J Nisbet and Shoba Ranganathan
    Citation: BMC Bioinformatics 2008 9(Suppl 1):S10
  10. The fast growing Protein Data Bank contains the three-dimensional description of more than 45000 protein- and nucleic-acid structures today. The large majority of the data in the PDB are measured by X-ray crys...

    Authors: Rafael Ördög, Zoltán Szabadka and Vince Grolmusz
    Citation: BMC Bioinformatics 2008 9(Suppl 1):S11
  11. The prediction of protein structure can be facilitated by the use of constraints based on a knowledge of functional sites. Without this information it is still possible to predict which residues are likely to ...

    Authors: Vijayalakshmi Chelliah and William R Taylor
    Citation: BMC Bioinformatics 2008 9(Suppl 1):S13
  12. G protein-coupled receptors (GPCRs) are abundant, activate complex signalling and represent the targets for up to ~60% of pharmaceuticals but there is a paucity of structural data. Bovine rhodopsin is the firs...

    Authors: Siavoush Dastmalchi, W Bret Church and Michael B Morris
    Citation: BMC Bioinformatics 2008 9(Suppl 1):S14
  13. Type I signal peptidases (SPases) are essential membrane-bound serine proteases responsible for the cleavage of signal peptides from proteins that are translocated across biological membranes. The crystal stru...

    Authors: Khar Heng Choo, Joo Chuan Tong and Shoba Ranganathan
    Citation: BMC Bioinformatics 2008 9(Suppl 1):S15
  14. Metabotropic glutamate receptors (mGluRs) are G protein coupled receptors that play important roles in synaptic plasticity and other neuro-physiological and pathological processes. Allosteric mGluR ligands are...

    Authors: Naveena Yanamala, Kalyan C Tirupula and Judith Klein-Seetharaman
    Citation: BMC Bioinformatics 2008 9(Suppl 1):S16
  15. The identification of mutations that confer unique properties to a pathogen, such as host range, is of fundamental importance in the fight against disease. This paper describes a novel method for identifying a...

    Authors: Olivo Miotto, AT Heiny, Tin Wee Tan, J Thomas August and Vladimir Brusic
    Citation: BMC Bioinformatics 2008 9(Suppl 1):S18
  16. T-cell epitopes that promiscuously bind to multiple alleles of a human leukocyte antigen (HLA) supertype are prime targets for development of vaccines and immunotherapies because they are relevant to a large p...

    Authors: Guang Lan Zhang, Asif M Khan, Kellathur N Srinivasan, AT Heiny, KX Lee, Chee Keong Kwoh, J Thomas August and Vladimir Brusic
    Citation: BMC Bioinformatics 2008 9(Suppl 1):S19
  17. Cyanobacteria are model organisms for studying photosynthesis, carbon and nitrogen assimilation, evolution of plant plastids, and adaptability to environmental stresses. Despite many studies on cyanobacteria, ...

    Authors: Woo-Yeon Kim, Sungsoo Kang, Byoung-Chul Kim, Jeehyun Oh, Seongwoong Cho, Jong Bhak and Jong-Soon Choi
    Citation: BMC Bioinformatics 2008 9(Suppl 1):S20
  18. Network Component Analysis (NCA) has shown its effectiveness in discovering regulators and inferring transcription factor activities (TFAs) when both microarray data and ChIP-on-chip data are available. Howeve...

    Authors: Chen Wang, Jianhua Xuan, Li Chen, Po Zhao, Yue Wang, Robert Clarke and Eric Hoffman
    Citation: BMC Bioinformatics 2008 9(Suppl 1):S21
  19. Preparedness for a possible global pandemic caused by viruses such as the highly pathogenic influenza A subtype H5N1 has become a global priority. In particular, it is critical to monitor the appearance of any...

    Authors: Dadabhai T Singh, Rahul Trehan, Bertil Schmidt and Timo Bretschneider
    Citation: BMC Bioinformatics 2008 9(Suppl 1):S23

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    Journal Impact Factor: 2.9
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