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Page 185 of 192

  1. Content type: Software

    Taxon specific hybridization probes in combination with a variety of commonly used hybridization formats nowadays are standard tools in microbial identification. A frequently applied technology, fluorescence in s...

    Authors: Yadhu Kumar, Ralf Westram, Sebastian Behrens, Bernhard Fuchs, Frank Oliver Glöckner, Rudolf Amann, Harald Meier and Wolfgang Ludwig

    Citation: BMC Bioinformatics 2005 6:61

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  2. Content type: Methodology article

    Development of robust and efficient methods for analyzing and interpreting high dimension gene expression profiles continues to be a focus in computational biology. The accumulated experiment evidence supports...

    Authors: Zheng Guo, Tianwen Zhang, Xia Li, Qi Wang, Jianzhen Xu, Hui Yu, Jing Zhu, Haiyun Wang, Chenguang Wang, Eric J Topol, Qing Wang and Shaoqi Rao

    Citation: BMC Bioinformatics 2005 6:58

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  3. Content type: Methodology article

    As the use of microarray technology becomes more prevalent it is not unusual to find several laboratories employing the same microarray technology to identify genes related to the same condition in the same sp...

    Authors: John R Stevens and RW Doerge

    Citation: BMC Bioinformatics 2005 6:57

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  4. Content type: Research article

    Regions of interest identified through genetic linkage studies regularly exceed 30 centimorgans in size and can contain hundreds of genes. Traditionally this number is reduced by matching functional annotation...

    Authors: Euan A Adie, Richard R Adams, Kathryn L Evans, David J Porteous and Ben S Pickard

    Citation: BMC Bioinformatics 2005 6:55

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  5. Content type: Methodology article

    Very few analytical approaches have been reported to resolve the variability in microarray measurements stemming from sample heterogeneity. For example, tissue samples used in cancer studies are usually contam...

    Authors: Harri Lähdesmäki, llya Shmulevich, Valerie Dunmire, Olli Yli-Harja and Wei Zhang

    Citation: BMC Bioinformatics 2005 6:54

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  6. Content type: Research article

    Gene duplication and gene loss during the evolution of eukaryotes have hindered attempts to estimate phylogenies and divergence times of species. Although current methods that identify clusters of orthologous ...

    Authors: Jaime E Blair, Prachi Shah and S Blair Hedges

    Citation: BMC Bioinformatics 2005 6:53

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  7. Content type: Software

    Normal mode analysis (NMA) has become the method of choice to investigate the slowest motions in macromolecular systems. NMA is especially useful for large biomolecular assemblies, such as transmembrane channe...

    Authors: Siv Midtun Hollup, Gisle Salensminde and Nathalie Reuter

    Citation: BMC Bioinformatics 2005 6:52

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  8. Content type: Software

    High throughput microarray analyses result in many differentially expressed genes that are potentially responsible for the biological process of interest. In order to identify biological similarities between g...

    Authors: Blaise TF Alako, Antoine Veldhoven, Sjozef van Baal, Rob Jelier, Stefan Verhoeven, Ton Rullmann, Jan Polman and Guido Jenster

    Citation: BMC Bioinformatics 2005 6:51

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  9. Content type: Research article

    Proteochemometrics is a new methodology that allows prediction of protein function directly from real interaction measurement data without the need of 3D structure information. Several reported proteochemometr...

    Authors: Eva Freyhult, Peteris Prusis, Maris Lapinsh, Jarl ES Wikberg, Vincent Moulton and Mats G Gustafsson

    Citation: BMC Bioinformatics 2005 6:50

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  10. Content type: Research article

    Popular methods to reconstruct molecular phylogenies are based on multiple sequence alignments, in which addition or removal of data may change the resulting tree topology. We have sought a representation of h...

    Authors: Olivier Bastien, Philippe Ortet, Sylvaine Roy and Eric Maréchal

    Citation: BMC Bioinformatics 2005 6:49

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  11. Content type: Software

    Many three-dimensional (3D) images are routinely collected in biomedical research and a number of digital atlases with associated anatomical and other information have been published. A number of tools are ava...

    Authors: Guangjie Feng, Nick Burton, Bill Hill, Duncan Davidson, Janet Kerwin, Mark Scott, Susan Lindsay and Richard Baldock

    Citation: BMC Bioinformatics 2005 6:47

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  12. Content type: Database

    wFleaBase is a database with the necessary infrastructure to curate, archive and share genetic, molecular and functional genomic data and protocols for an emerging model organism, the microcrustacean Daphnia. Com...

    Authors: John K Colbourne, Vasanth R Singan and Don G Gilbert

    Citation: BMC Bioinformatics 2005 6:45

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  13. Content type: Research article

    Gene expression analysis based on comparison of electrophoretic patterns is strongly dependent on the accuracy of DNA fragment sizing. The current normalization strategy based on molecular weight markers has l...

    Authors: Koji Kadota, Ryutaro Fukumura, Joseph J Rodrigue, Ryoko Araki and Masumi Abe

    Citation: BMC Bioinformatics 2005 6:43

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  14. Content type: Software

    Phages, viruses that infect prokaryotes, are the most abundant microbes in the world. A major limitation to studying these viruses is the difficulty of cultivating the appropriate prokaryotic hosts. One way ar...

    Authors: Florent Angly, Beltran Rodriguez-Brito, David Bangor, Pat McNairnie, Mya Breitbart, Peter Salamon, Ben Felts, James Nulton, Joseph Mahaffy and Forest Rohwer

    Citation: BMC Bioinformatics 2005 6:41

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  15. Content type: Methodology article

    Normalization is the process of removing non-biological sources of variation between array experiments. Recent investigations of data in gene expression databases for varying organisms and tissues have shown t...

    Authors: Tim Lu, Christine M Costello, Peter JP Croucher, Robert Häsler, Günther Deuschl and Stefan Schreiber

    Citation: BMC Bioinformatics 2005 6:37

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  16. Content type: Methodology article

    One important application of microarray experiments is to identify differentially expressed genes. Often, small and negative expression levels were clipped-off to be equal to an arbitrarily chosen cutoff value...

    Authors: Markus Neuhäuser, Tanja Boes and Karl-Heinz Jöckel

    Citation: BMC Bioinformatics 2005 6:35

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  17. Content type: Database

    We present a biological data warehouse called Atlas that locally stores and integrates biological sequences, molecular interactions, homology information, functional annotations of genes, and biological ontolo...

    Authors: Sohrab P Shah, Yong Huang, Tao Xu, Macaire MS Yuen, John Ling and BF Francis Ouellette

    Citation: BMC Bioinformatics 2005 6:34

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  18. Content type: Research article

    Detection of DNA-binding sites in proteins is of enormous interest for technologies targeting gene regulation and manipulation. We have previously shown that a residue and its sequence neighbor information can...

    Authors: Shandar Ahmad and Akinori Sarai

    Citation: BMC Bioinformatics 2005 6:33

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  19. Content type: Methodology article

    Wise et al. introduced a rank-based statistical technique for meta-analysis of genome scans, the Genome Scan Meta-Analysis (GSMA) method. Levinson et al. recently described two generalizations of the GSMA stat...

    Authors: James A Koziol and Anne C Feng

    Citation: BMC Bioinformatics 2005 6:32

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  20. Content type: Research article

    Cellular processes require the interaction of many proteins across several cellular compartments. Determining the collective network of such interactions is an important aspect of understanding the role and re...

    Authors: Harold J Drabkin, Christopher Hollenbeck, David P Hill and Judith A Blake

    Citation: BMC Bioinformatics 2005 6:29

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  21. Content type: Research article

    Normalization is a critical step in analysis of gene expression profiles. For dual-labeled arrays, global normalization assumes that the majority of the genes on the array are non-differentially expressed betw...

    Authors: Yingdong Zhao, Ming-Chung Li and Richard Simon

    Citation: BMC Bioinformatics 2005 6:28

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  22. Content type: Research article

    Microarray-CGH experiments are used to detect and map chromosomal imbalances, by hybridizing targets of genomic DNA from a test and a reference sample to sequences immobilized on a slide. These probes are geno...

    Authors: Franck Picard, Stephane Robin, Marc Lavielle, Christian Vaisse and Jean-Jacques Daudin

    Citation: BMC Bioinformatics 2005 6:27

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  23. Content type: Research article

    A critical step in processing oligonucleotide microarray data is combining the information in multiple probes to produce a single number that best captures the expression level of a RNA transcript. Several sys...

    Authors: Kerby Shedden, Wei Chen, Rork Kuick, Debashis Ghosh, James Macdonald, Kathleen R Cho, Thomas J Giordano, Stephen B Gruber, Eric R Fearon, Jeremy MG Taylor and Samir Hanash

    Citation: BMC Bioinformatics 2005 6:26

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  24. Content type: Research article

    Alternative splicing (AS) is now considered as a major actor in transcriptome/proteome diversity and it cannot be neglected in the annotation process of a new genome. Despite considerable progresses in term of...

    Authors: Sylvain Foissac and Thomas Schiex

    Citation: BMC Bioinformatics 2005 6:25

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  25. Content type: Research article

    Current protein clustering methods rely on either sequence or functional similarities between proteins, thereby limiting inferences to one of these areas.

    Authors: Victor Kunin and Christos A Ouzounis

    Citation: BMC Bioinformatics 2005 6:24

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  26. Content type: Research article

    Post-translational modification by Small Ubiquitin-like Modifiers (SUMO) has been implicated in protein targeting, in the maintenance of genomic integrity and in transcriptional control. But the specific molec...

    Authors: Maria Novatchkova, Andreas Bachmair, Birgit Eisenhaber and Frank Eisenhaber

    Citation: BMC Bioinformatics 2005 6:22

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  27. Content type: Software

    The large amount of data that are currently produced in the biological sciences can no longer be explored and visualized efficiently with traditional, specialized software. Instead, new capabilities are needed...

    Authors: John L Moreland, Apostol Gramada, Oleksandr V Buzko, Qing Zhang and Philip E Bourne

    Citation: BMC Bioinformatics 2005 6:21

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  28. Content type: Methodology article

    The process of oxidative folding combines the formation of native disulfide bond with conformational folding resulting in the native three-dimensional fold. Oxidative folding pathways can be described in terms...

    Authors: Vilmos Ágoston, Masa Cemazar, László Kaján and Sándor Pongor

    Citation: BMC Bioinformatics 2005 6:19

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  29. Content type: Software

    Detection of Loss of Heterozygosity (LOH) is one of the most common molecular applications in the study of human diseases, in particular cancer. The technique is commonly used to examine whether a known tumour...

    Authors: Rifat A Hamoudi, Amina El-Hamidi and Ming-Qing Du

    Citation: BMC Bioinformatics 2005 6:18

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  30. Content type: Research article

    Enzyme-linked immunosorbent assay (ELISA) is a standard immunoassay to estimate a protein's concentration in a sample. Deploying ELISA in a microarray format permits simultaneous estimation of the concentratio...

    Authors: Don Simone Daly, Amanda M White, Susan M Varnum, Kevin K Anderson and Richard C Zangar

    Citation: BMC Bioinformatics 2005 6:17

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  31. Content type: Methodology article

    Searching a biological sequence database with a query sequence looking for homologues has become a routine operation in computational biology. In spite of the high degree of sophistication of currently availab...

    Authors: Antje Krause, Jens Stoye and Martin Vingron

    Citation: BMC Bioinformatics 2005 6:15

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2018 Journal Metrics

  • Citation Impact
    2.511 - 2-year Impact Factor
    2.970 - 5-year Impact Factor
    0.855 - Source Normalized Impact per Paper (SNIP)
    1.374 - SCImago Journal Rank (SJR)


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