Prediction of nuclear proteins using SVM and HMM models

BMC Bioinformatics

Table 4 The performance of nuclear protein prediction methods on 2213 human proteins (1526 non-nuclear and 687 nuclear).

Method	Sensitivity	PPV (Probability of correct prediction of nuclear proteins)
NucPred (0.8 threshold)	0.31	0.62
NucPred (0.5 threshold)	0.63	0.48
PredictNLS	0.23	0.63
PSORT II	0.70	0.47
NucPred (0.8) AND PredictNLS	0.17	0.73
NucPred (0.8) OR PredictNLS	0.43	0.57
LOCtree	0.63	0.59
BaCelLo	0.61	0.67
NpPred	0.83	0.63

PPV = Tp/Tp+Fp; Tp = True positive predictions; Fp = False positive predictions.

ISSN: 1471-2105