Figure 5
From: TIde: a software for the systematic scanning of drug targets in kinetic network models
Simulated titration of the modifier in the Trypanosoma model. Depicted is the change in the objective function, which is the steady state flux through the upper glycolysis (reference flux ≈ 90). The first diagram depicts the effect of noncompetitive inhibitions in different positions in the network. In the second diagramm, effects of different inhibition types on the hexokinase are shown.