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Figure 1 | BMC Bioinformatics

Figure 1

From: Prediction of hot spot residues at protein-protein interfaces by combining machine learning and energy-based methods

Figure 1

Schematic overview of protein structural regions which define the different energy contributions. The red filled area, (a), corresponds to side-chain atoms of the mutated residue; the red and blue striped regions, (b) and (c) respectively, correspond to atoms within 10 Å of the C β of the mutated residue. We distinguish 3 types of interactions: side-chain inter-molecular between (a) and (c), environment inter-molecular between (b) and (c), side-chain intra-molecular between (a) and (b).

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