Figure 1From: Gene set-based module discovery in the breast cancer transcriptomeSchema of systematic search for expression modules. We prepared a collection of seed gene sets based on cis-regulatory motifs, ChIP-chip and gene locus information. We next statistically evaluated whether each seed gene set includes a significant large number of coherently expressed genes in expression profile data. If such a coherently expressed gene subset exists, we assumed it as an expression module, and obtained its averaged expression profile as an activity profile.Back to article page