Table 1 Distribution of molecules following Lipinski's rule.
From: Physicochemical property space distribution among human metabolites, drugs and toxins
Datasets | Lipinski Properties | |||
|---|---|---|---|---|
| Â | Molecular weight <500 Da | H-bond Donor <=5 | H-bond Acceptor <=10 | Log P <5 |
HMDB (Metabolites) | 34% | 84% | 84% | 35% |
DDB (Drugs) | 84% | 86% | 87% | 92% |
CPDB (Toxins) | 94% | 98% | 97% | 92% |