Figure 5
From: Pairwise and higher-order correlations among drug-resistance mutations in HIV-1 subtype B protease
The Shannon entropy for the family of all triplet distributions having the same univariate and bivariate marginals as the data for the triplet 46-54-90 (PI2+ cohort) plotted as a function of the parameter α defined in Equation 8. The observed distribution is indicated by the filled circle, and the entropies of the independent model (S
ind
), the model with only pair interactions (S
pair
) and the observed data (S
obs
) are indicated, as well as I
multi
and the connected information measures 
and 
. S
pair
is the entropy of the distribution denoted by 
(A, B, C) in the text which has the maximum entropy subject to the constraints that all of the univariate and bivariate marginals are the same as the observed distribution, and is denoted in the figure by a star.