From: Annotation of protein residues based on a literature analysis: cross-validation against UniProtKb
MAN | FEAT | ||
---|---|---|---|
Category | Defintion | Category | Defintion |
STR_COMP | Structure component. Class denoting concepts that represent pieces and parts of the protein structure. | DOMAIN | Extent of a domain, which is defined as a specific combination of secondary structures organised into a characteristic three-dimensional structure of fold. |
 |  | MOTIF | Short (up to 20 amino acids) sequence motif of biological interest. |
 |  | TOPO_DOM | Topological domain. |
 |  | CHAIN | Extent of a polypeptide chain in the mature protein. |
 |  | TRANSMEM | Extent of a transmembrane region. |
 |  | COILED | Extent of a coiled-coil region. |
CHEM_MOD | Chemical modification. Class denoting changes to the protein sequence and the chemical composition. | VARIANT | Authors report that sequence variants exist. |
 |  | MOD_RES | Posttranslational modification of a residue. |
 |  | PEPTIDE | Extent of a released active peptide. |
 |  | VAR_SEQ | Description of sequence variants produced by alternative splicing, alternative promoter usage, alternative initiation and ribosomal frameshifting. |
 |  | LIPID | Covalent binding of a lipid moiety. |
 |  | CARBOHYD | Glycosylation site. |
STR_MOD | Structural modification. Class denoting the changes to the protein structure without changes to the chemical composition. | REGION | Extent of a region of interest in the sequence. |
 |  | SITE | Any interesting single amino-acid site on the sequence, that is not defined by another feature key. |
BINDING | Binding type. Class denoting different physico-chemical forces leading to a bond formation between a protein structure component and a chemical entity. | BINDING | Binding site for any chemical group (co-enzyme, prosthetic group, etc.). |
 |  | METAL | Binding site for a metal ion. |
 |  | DISULFID | Disulfide bond. |
 |  | CROSSLNK | Posttranslationally formed amino acid bonds. |
 |  | DNA_BIND | Extent of a DNA-binding region. |
 |  | NP_BIND | Extent of a nucleotide phosphate-binding region. |
 |  | ZN_FING | Extent of a zinc finger region. |
 |  | CA_BIND | Extent of a calcium-binding region. |
ENZ_ACT | Enzymatic activity. Types of enzymatic reactions as a subpart to protein functions. | ACT_SITE | Amino acid(s) involved in the activity of an enzyme. |
CELL | Cellular phenotype. Class denoting different cellular phenotypes that can be affected by structural or compositional changes of a protein. | N/A | Â |