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Figure 5 | BMC Bioinformatics

Figure 5

From: TimeDelay-ARACNE: Reverse engineering of gene networks from time-course data by an information theoretic approach

Figure 5

Yeast Synthetic Network and TimeDelay-ARACNE predicted Yeast Synthetic Network on the Switched ON dataset. a) the true Yeast Synthetic Network true; b) the TimeDelay-ARACNE inferred graph; c) is the true Yeast Synthetic Network simplified; d) is the TimeDelay-ARACNE inferred graph on simplifed network. In b) TimeDelay-ARACNE correctly recovers 5 edges, 1 edge has wrong direction, 1 is a false positive and 2 edges are missing even if the GAL4→-GAL80 connection is a protein-protein connection like GAL80→GAL4 (which is present anyway) and can't have versus. In d) TimeDelay-ARACNE recovers 4 edges correctly, 1 is a false positive and 2 edges are missing even if GAL4/GAL80→SWI5 connection is a 2 genes auto regulation connection that is not treated in our algorithm. Here we represent true positives as straight connections, dotted lines are false positives, false negatives are not reported. Missing verse on the connection means that the algorithm recovers the wrong verse.

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