Table 3 ROSA-based sensitivity analysis results for the integrated response of ERK-PP activity.

Reaction

MC

DA

PA

GHI

OHA

Reaction

MC

DA

PA

GHI

OHA

4

39

39

39

39

39

4

1

0

0

0

0

6

26

27

27

27

27

6

1

0

0

0

0

11

9

10

9

9

9

11

0

0

0

0

0

13

8

8

8

8

8

13

0

0

0

0

0

SESI - I-RESPONSE ( λ ^‡ = 0.2)

JESI - I-RESPONSE ( λ ^‡ = 0.2)

Reaction

MC

DA

PA

GHI

OHA

Reaction

MC

DA

PA

GHI

OHA

4

37

38

40

40

39

4

5

1

1

2

2

6

25

27

26

26

25

6

4

0

0

1

1

8

5

5

5

5

6

8

2

0

0

1

1

11

7

9

8

8

8

11

1

0

0

0

0

13

6

8

7

7

7

13

1

1

0

0

0

SESI - I-RESPONSE ( λ ^‡ = 0.3)

JESI - I-RESPONSE ( λ ^‡ = 0.3)

Reaction

MC

DA

PA

GHI

OHA

Reaction

MC

DA

PA

GHI

OHA

4

38

37

43

41

36

4

10

2

9

10

11

6

21

26

22

21

21

6

7

1

4

4

6

8

8

4

7

7

7

8

4

0

3

4

5

SESI - I-RESPONSE ( λ ^‡ = 0.4)

JESI - I-RESPONSE ( λ ^‡ = 0.4)

Reaction

MC

DA

PA

GHI

OHA

Reaction

MC

DA

PA

GHI

OHA

4

36

36

43

40

34

4

15

3

18

15

16

6

18

25

16

19

18

6

8

2

7

7

8

8

8

4

8

9

8

8

7

1

6

6

7