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Table 5 The performance of GPCR-SVMFS and GPCRPred at subfamily level

From: Classification of G-protein coupled receptors based on support vector machine with maximum relevance minimum redundancy and genetic algorithm

Class A subfamilies

Number of proteins

Q i /Q(%)

  

GPCRPred[14]

GPCR-SVMFS a

Amine

221

99.10

100.0

Peptide

381

99.70

99.21

Hormone

25

100.0

100.0

Rhodopsin

183

98.90

99.45

Olfactory

87

100.0

100.0

Prostanoid

38

100.0

100.0

Nucleotide

48

85.40

93.75

Cannabis

11

100.0

90.91

Platelet activating factor

4

100.0

100.0

Gonadotrophin releasing hormone

10

100.0

100.0

Thyrotropin releasing hormone

7

85.70

85.71

Melatonin

13

100.0

100.0

Viral

17

33.30

76.47

Lysospingolipids

9

58.80

100.0

Overall

1054

97.30

98.77

  1. a In order to consistent with evaluation method of GPCRPred, 2-fold cross-validation is utilized.