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Table 1 Seven amino acid classes used in our model.

From: Interaction prediction and classification of PDZ domains

Class

Amino acid(s)

Volume (Ã…3)

Dipole (Debye)

1

Ala, Gly, Val

<50

0

2

Ile, Leu, Phe, Pro

>50

0

3

Tyr, Met, Thr, Ser

>50

<1.0

4

His, Asn, Gln, Trp

>50

1.0 < Dip. < 2.0

5

Arg, Lys

>50

2.0 < Dip. < 3.0

6

Asp, Glu

>50

>3.0

7

Cys*

>50

<1.0

  1. *Cys is differentiated from class 3 because it can form disulfide bonds