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Table 2 Comparison of prediction results for the RTA method, described in this article, and the SMM-align method

From: Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model

 

AUC

 

MHC allele

RTA

SMM-Align

Number of data

DRB1*0101

0.748

0.702

1203

DRB1*0301

0.843

0.779

474

DRB1*0401

0.779

0.741

457

DRB1*0404

0.829

0.798

168

DRB1*0405

0.823

0.727

171

DRB1*0701

0.813

0.768

310

DRB1*0802

0.806

0.724

174

DRB1*0901

0.752

0.726

117

DRB1*1101

0.829

0.715

359

DRB1*1302

0.882

0.810

179

DRB1*1501

0.792

0.715

365

DRB3*0101

0.960

0.620

102

DRB4*0101

0.820

0.730

181

DRB5*0101

0.772

0.664

343

H2-IAb

0.926

0.913

76

H2-IAd

0.894

0.819

342

H2-IAs

0.891

0.877

126

  1. The RTA results were calculated using the cross-validation sets from Ref. [18]. The SMM-align results were taken from the same reference.
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BMC Bioinformatics

ISSN: 1471-2105

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