Computing H/D-Exchange rates of single residues from data of proteolytic fragments

BMC Bioinformatics

Table 3 Comparison with NMR

Dataset	Single solution	Majority Vote	Arithmetic Mean
CytoC	77.87	69.45	69.45
FKBP V1 (ilp)	58.03	67.09	74.69
FKBP V2 (mem)	67.09	67.68	67.09
FKBP V3 (xiii)	75	71.88	70.32
FKBP V4 (both)	58.03	62.97	64.20

Comparison of our results to those obtained by NMR. The error measure is based on an comparison per part, hence taking the sequence positions into account. To obtain an unique answer, we used two methods to average over all solutions, namely taking the majority and the average. Then we counted the percentage of amino acids that have the same exchange rates in both methods, according to the optimal reordering within the parts of equivalent residues.

ISSN: 1471-2105