|  |  | Methods |  |  |  |
---|
 |
EDR
|
Bonf
|
BH
|
BY
|
qvalue
|
rawp
|
DEGs | 1070 | 606 | 1420 | 974 | 1734 | 1833 |
TP | 90 | 63 | 101 | 83 | 106 | 109 |
FP | 980 | 543 | 1319 | 891 | 1628 | 1724 |
TN | 3774 | 4238 | 3424 | 3870 | 3110 | 3011 |
FN | 91 | 118 | 80 | 98 | 75 | 72 |
TPR | 0.4972 | 0.3481 | 0.5580 | 0.4586 | 0.5856 | 0.6022 |
FPR | 0.2061 | 0.1136 | 0.2781 | 0.1871 | 0.3436 | 0.3641 |
- The expression data set was downloaded from http://www.ambystoma.org and was preprocessed by the RMA method [38]. Differentially expressed genes (DEGs) were detected at the significance level of 0.05 by the EDR method and the other methods from the multtest package [39]. The resultant DEGs were compared with the true DEGs (TP) measured by digital expression. False positives (FP) are those DEGs that are not found to be differential in digital expression analysis. True negatives (TN) are those genes that are not differential in both platforms.