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Figure 4 | BMC Bioinformatics

Figure 4

From: Bi-directional gene set enrichment and canonical correlation analysis identify key diet-sensitive pathways and biomarkers of metabolic syndrome

Figure 4

Top 20 regulated KEGG pathways in adipose (A) liver (L) and muscle (M) in response to feeding obese, diabetic ob/ob mice a CLA-enriched beef diet that improved plasma markers associated with metabolic health. Heatmap colours indicate pathway-level t-statistics. Yellow: up-regulated; blue: down-regulated. Grey triangles indicate pathways wherein bidirectional, but not single direction enrichment, reached significance (α = 0.05; adjusted for multiple testing). Values indicate percentage of up-regulated and down-regulated genes among those with raw p-value < 0.05.

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BMC Bioinformatics

ISSN: 1471-2105

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