Gene
|
Chr
|
Start
|
End_pos
|
SNPs/rvSNPs
|
QT+RV
|
QT-RV
|
QT+RV mean
|
QT-RV mean
|
p-val
|
BetaCoef
|
St.Er
|
[lowCI - upCI]
|
t-test
|
t-test_p-val
|
---|
MIB2 | 1 | 0 | 107622 | (10/1) | 106 | 1125 | -0.367 | 0.037 | 6.77E-05 | 0.404 | 0.101 | [0.206 - 0.602] | -3.975 | 3.72E-05 |
GOLGA8C | 15 | 18977714 | 19091040 | (29/4) | 127 | 1097 | -0.347 | 0.042 | 3.19E-05 | 0.389 | 0.093 | [0.206 - 0.571] | -4.149 | 1.78E-05 |
TPO | 2 | 1346242 | 1575502 | (29/6) | 70 | 1158 | 0.478 | -0.028 | 4.00E-05 | -0.506 | 0.122 | [-0.746 - -0.266] | 4.107 | 1.80E-05 |
EXOC3 | 5 | 446375 | 570407 | (24/1) | 4 | 1228 | 1.935 | -0.006 | 1.00E-04 | -1.941 | 0.498 | [-2.918 - -0.964] | 3.874 | 5.12E-05 |
C10orf110 | 10 | 1008606 | 1130138 | (66/4) | 111 | 1116 | 0.379 | -0.036 | 4.00E-05 | -0.415 | 0.099 | [-0.609 - -0.221] | 4.161 | 1.48E-05 |
- This file provides summary statistics for all genes that achieved a p value ≤ the p value set by the -pout command line option. The summary file is a tab-delimited file with 15 columns: Gene/Window name, Chromosome, Starting bp position, End bp position, Number of SNPs in the Gene/Window, Number of individuals with low frequency/rare variant minor alleles, Number of individuals without low frequency/rare variant minor alleles, The mean QT value of individuals with low frequency/rare variant minor alleles, The mean QT value of individuals without low frequency/rare variant minor alleles, The p value of the linear regression, The Beta coefficient from the linear regression, The Standard Error of the Beta Coefficient, the lower and upper 95% confidence intervals of Beta, The t-statistic, and The t-statistic p value.