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Table 2 The distribution of structural topology on 40 transmembrane proteins that are extracted from release 15.0 of UniProt.

From: Incorporating significant amino acid pairs to identify O-linked glycosylation sites on transmembrane proteins and non-transmembrane proteins

UniProt ID

Sequence length

Protein name

Number of TM segment

Percentage of sequence length in specific structural topology

    

L

N

E

C

TM

S

Unknown

O08984

620

Lamin-B receptor

TM = 8

0.0%

34.4%

0.0%

0.0%

27.4%

0.0%

38.2%

O14786

923

Neuropilin-1

TM = 1

0.0%

0.0%

90.5%

4.8%

2.5%

2.3%

0.0%

O15431

190

High affinity copper uptake protein 1

TM = 3

0.0%

0.0%

33.7%

33.2%

33.2%

0.0%

0.0%

P01375

233

Tumor necrosis factor

TM = 1

0.0%

0.0%

76%

15%

9%

0.0%

0.0%

P01589

272

Interleukin-2 receptor alpha chain

TM = 1

0.0%

0.0%

80.5%

4.8%

7%

7.7%

0.0%

P01867

404

Ig gamma-2B chain C region

TM = 1

0.0%

0.0%

86.6%

8.9%

4.5%

0.0%

0.0%

P02724

150

Glycophorin-A

TM = 1

0.0%

0.0%

48%

24%

15.3%

12.7%

0.0%

P02725

133

Glycophorin-A

TM = 1

0.0%

0.0%

46.6%

39.0.0%

17.3%

0.0%

0.0%

P02726

120

Glycophorin-A

TM = 1

0.0%

0.0%

40.8%

40.0%

19.2%

0.0%

0.0%

P02727

129

Glycophorin-A

TM = 1

0.0%

0.0%

50.4%

20.2%

16.3%

13.2%

0.0%

P02786

760

Transferrin receptor protein 1

TM = 1

0.0%

0.0%

88.4%

8.8%

2.8%

0.0%

0.0%

P03138

389

Large envelope protein

TM = 4

0.0%

0.0%

63.2%

14.7%

22.1%

0.0%

0.0%

P04441

279

H-2 class II histocompatibility antigen gamma chain

TM = 1

0.0%

0.0%

80.3%

10.4%

9.3%

0.0%

0.0%

P04921

128

Glycophorin-C

TM = 1

0.0%

0.0%

44.5%

36.7%

18.8%

0.0%

0.0%

P05067

770

Amyloid beta A4 protein

TM = 1

0.0%

0.0%

88.6%

6.1%

3.1%

2.2%

0.0%

P06028

91

Glycophorin-B

TM = 1

0.0%

0.0%

44%

11%

24.2%

20.9%

0.0%

P07204

575

Thrombomodulin

TM = 1

0.0%

0.0%

86.4%

6.3%

4.2%

3.1%

0.0%

P07359

626

Platelet glycoprotein Ib alpha chain

TM = 1

0.0%

0.0%

78.1%

16%

3.4%

2.6%

0.0%

P07725

236

T-cell surface glycoprotein CD8 alpha chain

TM = 1

0.0%

0.0%

69.1%

11%

8.9%

11%

0.0%

P08514

1039

Integrin alpha-IIb

TM = 1

0.0%

0.0%

92.6%

1.9%

2.5%

3%

0.0%

P08592

770

Amyloid beta A4 protein

TM = 1

0.0%

0.0%

88.6%

6.1%

3.1%

2.2%

0.0%

P11279

417

Lysosome-associated membrane glycoprotein 1

TM = 1

84.9%

0.0%

0.0%

2.9%

5.5%

6.7%

0.0%

P13473

410

Lysosome-associated membrane glycoprotein 2

TM = 1

84.6%

0.0%

0.0%

2.7%

5.9%

6.8%

0.0%

P13838

378

Leukosialin

TM = 1

0.0%

0.0%

59.6%

32.8%

6.1%

1.9%

0.0%

P14221

144

Glycophorin-A

TM = 1

0.0%

0.0%

47.9%

36.1%

16.0.0%

0.0%

0.0%

P16150

400

Leukosialin

TM = 1

0.0%

0.0%

58.2%

31%

5.8%

4.8%

0.0%

P17404

335

Chondromodulin-1

TM = 1

0.0%

0.0%

0.0%

0.0%

6.3%

0.0%

93.7%

P21583

273

Kit ligand

TM = 1

0.0%

0.0%

69.2%

13.2%

8.4%

9.2%

0.0%

P42098

421

Zona pellucida sperm-binding protein 3

TM = 1

0.0%

0.0%

85.3%

4.5%

5.0.0%

5.2%

0.0%

P51681

352

C-C chemokine receptor type 5

TM = 7

0.0%

0.0%

26.1%

27.0.0%

46.9%

0.0%

0.0%

P61073

352

C-X-C chemokine receptor type 4

TM = 7

0.0%

0.0%

281%

29.8%

42.0.0%

0.0%

0.0%

P80370

383

Protein delta homolog 1

TM = 1

0.0%

0.0%

73.1%

14.6%

6.3%

6.0.0%

0.0%

Q00657

2326

Chondroitin sulfate proteoglycan 4

TM = 1

0.0%

0.0%

94.4%

3.3%

1.1%

1.2%

0.0%

Q01455

230

Membrane protein

TM = 3

17.0.0%

0.0%

0.0%

57.4%

25.7%

0.0%

0.0%

Q07287

536

Zona pellucida sperm-binding protein 4

TM = 1

0.0%

0.0%

91.4%

0.7%

3.9%

3.9%

0.0%

Q09163

385

Protein delta homolog 1

TM = 1

0.0%

0.0%

73.2%

14.5%

6.2%

6.0.0%

0.0%

Q16790

459

Carbonic anhydrase 9

TM = 1

0.0%

0.0%

82.1%

5.2%

4.6%

8.1%

0.0%

Q62765

843

Neuroligin-1

TM = 1

0.0%

0.0%

77.3%

14.8%

2.5%

5.3%

0.0%

Q71M36

566

Chondroitin sulfate proteoglycan 5

TM = 1

0.0%

0.0%

69.4%

21.6%

3.7%

5.3%

0.0%

Q99075

208

Proheparin-binding EGF-like growth factor

TM = 1

0.0%

0.0%

67.8%

11.5%

11.5%

9.1%

0.0%

  1. Abbreviation: L, Lumenal; N, Nucleoplasmic; E, Extracellular; C, Cytoplasmic; TM, Transmembrane; S, Signal peptide.