From: Peptide binding predictions for HLA DR, DP and DQ molecules
Allelic variant | ARB | SMM-align | PROPRED | combinatorial library | NN-align | Consensus | Consensus-best32 | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | ALL | SR 1 | ALL | SR 1 | ALL | SR 1 | ALL | SR 1 | ALL | SR 1 | ALL | SR 1 | ALL | SR 1 |
HLA-DPA1*0103-DPB1*0201 | 0.823 | 0.745 | 0.921 | 0.767 | Â | Â | 0.840 | 0.724 | 0.943 | 0.793 | 0.932 | 0.809 | 0.935 | 0.796 |
HLA-DPA1*01-DPB1*0401 | 0.847 | 0.746 | 0.930 | 0.767 | Â | Â | 0.833 | 0.704 | 0.947 | 0.802 | 0.938 | 0.803 | 0.941 | 0.794 |
HLA-DPA1*0201-DPB1*0101 | 0.824 | 0.743 | 0.909 | 0.786 | Â | Â | 0.849 | 0.723 | 0.944 | 0.818 | 0.927 | 0.818 | 0.932 | 0.819 |
HLA-DPA1*0201-DPB1*0501 | 0.859 | 0.709 | 0.923 | 0.728 | Â | Â | 0.867 | 0.729 | 0.956 | 0.787 | 0.942 | 0.781 | 0.946 | 0.782 |
HLA-DPA1*0301-DPB1*0402 | 0.821 | 0.771 | 0.932 | 0.818 | Â | Â | 0.864 | 0.756 | 0.949 | 0.828 | 0.938 | 0.841 | 0.941 | 0.830 |
HLA-DQA1*0101-DQB1*0501 | 0.871 | 0.741 | 0.930 | 0.783 | Â | Â | 0.809 | 0.728 | 0.945 | 0.805 | 0.933 | 0.809 | 0.942 | 0.811 |
HLA-DQA1*0102-DQB1*0602 | 0.777 | 0.708 | 0.838 | 0.734 | Â | Â | 0.765 | 0.752 | 0.880 | 0.762 | 0.851 | 0.778 | 0.859 | 0.779 |
HLA-DQA1*0301-DQB1*0302 | 0.748 | 0.637 | 0.807 | 0.663 | Â | Â | 0.698 | 0.616 | 0.851 | 0.693 | 0.823 | 0.690 | 0.837 | 0.692 |
HLA-DQA1*0401-DQB1*0402 | 0.845 | 0.643 | 0.896 | 0.761 | Â | Â | 0.681 | 0.637 | 0.922 | 0.742 | 0.908 | 0.749 | 0.916 | 0.762 |
HLA-DQA1*0501-DQB1*0201 | 0.855 | 0.700 | 0.901 | 0.736 | Â | Â | 0.586 | 0.620 | 0.932 | 0.777 | 0.917 | 0.774 | 0.923 | 0.779 |
HLA-DQA1*0501-DQB1*0301 | 0.844 | 0.756 | 0.910 | 0.801 | Â | Â | 0.802 | 0.745 | 0.927 | 0.811 | 0.917 | 0.814 | 0.919 | 0.816 |
HLA-DRB1*0101 | 0.770 | 0.710 | 0.798 | 0.756 | 0.720 | 0.692 | 0.739 | 0.697 | 0.843 | 0.763 | 0.810 | 0.759 | 0.820 | 0.769 |
HLA-DRB1*0301 | 0.753 | 0.728 | 0.852 | 0.808 | 0.699 | 0.669 | Â | Â | 0.887 | 0.829 | 0.862 | 0.823 | 0.873 | 0.835 |
HLA-DRB1*0401 | 0.731 | 0.668 | 0.781 | 0.721 | 0.737 | 0.711 | Â | Â | 0.813 | 0.734 | 0.799 | 0.735 | 0.804 | 0.738 |
HLA-DRB1*0404 | 0.707 | 0.681 | 0.816 | 0.789 | 0.769 | 0.753 | Â | Â | 0.823 | 0.803 | 0.826 | 0.800 | 0.831 | 0.809 |
HLA-DRB1*0405 | 0.771 | 0.716 | 0.822 | 0.767 | 0.767 | 0.742 | Â | Â | 0.870 | 0.794 | 0.847 | 0.797 | 0.851 | 0.797 |
HLA-DRB1*0701 | 0.767 | 0.736 | 0.834 | 0.796 | 0.773 | 0.750 | 0.762 | 0.729 | 0.869 | 0.811 | 0.851 | 0.806 | 0.858 | 0.808 |
HLA-DRB1*0802 | 0.702 | 0.649 | 0.741 | 0.689 | 0.647 | 0.641 | Â | Â | 0.796 | 0.698 | 0.772 | 0.708 | 0.778 | 0.710 |
HLA-DRB1*0901 | 0.747 | 0.654 | 0.765 | 0.696 | Â | Â | 0.572 | 0.553 | 0.810 | 0.713 | 0.801 | 0.716 | 0.796 | 0.716 |
HLA-DRB1*1101 | 0.800 | 0.777 | 0.864 | 0.829 | 0.804 | 0.779 | Â | Â | 0.900 | 0.847 | 0.880 | 0.850 | 0.885 | 0.854 |
HLA-DRB1*1302 | 0.727 | 0.667 | 0.797 | 0.754 | 0.600 | 0.577 | Â | Â | 0.814 | 0.732 | 0.796 | 0.742 | 0.811 | 0.757 |
HLA-DRB1*1501 | 0.763 | 0.696 | 0.796 | 0.741 | 0.743 | 0.703 | Â | Â | 0.852 | 0.756 | 0.820 | 0.756 | 0.827 | 0.758 |
HLA-DRB3*0101 | 0.709 | 0.678 | 0.819 | 0.780 | Â | Â | 0.655 | 0.655 | 0.856 | 0.798 | 0.834 | 0.787 | 0.844 | 0.799 |
HLA-DRB4*0101 | 0.785 | 0.747 | 0.816 | 0.762 | Â | Â | 0.697 | 0.691 | 0.870 | 0.789 | 0.844 | 0.791 | 0.846 | 0.784 |
HLA-DRB5*0101 | 0.760 | 0.697 | 0.832 | 0.776 | 0.728 | 0.711 | Â | Â | 0.886 | 0.795 | 0.848 | 0.786 | 0.851 | 0.798 |
H-2-IAb | 0.800 | 0.775 | 0.855 | 0.830 | Â | Â | Â | Â | 0.858 | 0.847 | 0.853 | 0.846 | 0.866 | 0.847 |
Average | 0.785 | 0.711 | 0.850 | 0.763 | 0.726 | 0.703 | 0.751 | 0.691 | 0.882 | 0.782 | 0.864 | 0.783 | 0.871 | 0.786 |
Min | 0.702 | 0.637 | 0.741 | 0.663 | 0.600 | 0.577 | 0.572 | 0.553 | 0.796 | 0.693 | 0.772 | 0.690 | 0.778 | 0.692 |
Max | 0.871 | 0.777 | 0.932 | 0.830 | 0.804 | 0.779 | 0.867 | 0.756 | 0.956 | 0.847 | 0.942 | 0.850 | 0.946 | 0.854 |