Skip to main content

Table 1 Selected parameters for the different combination of scoring terms.

From: Linear predictive coding representation of correlated mutation for protein sequence alignment

Method

Parameters

Average MaxSub

 

w mut

w sec

w cor

d 0

g open

g ext

Base

 

PPA

1.0

-

-

-

6.0

0.5

0.5

0.3099

PPA_SS

1.0

1.5

-

-

5.0

0.5

0.0

0.3183

CMPA

-

-

1.0

2.8

7.0

1.7

0.5

0.2873

CMPA_PPA

1.0

-

0.5

3.2

8.0

0.4

1.0

0.3291

CMPA_PPA_SS

1.0

1.5

0.5

3.2

8.0

0.6

0.0

0.3334

  1. w mut , w sec , w cor , and d0 denote the corresponding notations in alignment score function, and g open , g ext , and base denote gap-open cost, gap-extension cost, and baseline parameter used for dynamic programming procedure. PPA and PPA_SS denote profile-profile alignment without and with secondary structure prediction, respectively, CMPA denote alignment solely using CM profile, and CMPA_PPA and CMPA_PPA_SS denote alignment combining CM profile with PPA and PPA_SS, respectively.