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Table 2 Amino acid frequency distributions of similar IDD clusters

From: Intrinsically disordered domains deviate significantly from random sequences in mammalian proteins

Cluster

A

R

N

D

C

Q

E

G

H

I

L

K

M

F

P

S

T

W

Y

V

Immune (0)

11

6

2

5

1

5

14

4

2

2

12

7

2

1

5

10

4

0

1

4

Non-Immune (99)

7

5

4

5

1

8

14

3

2

3

13

10

2

1

2

7

5

0

2

5

Immune (1)

8

5

2

5

1

5

7

11

2

2

7

5

2

2

12

11

6

1

2

4

Non-Immune (18)

7

6

3

4

1

5

6

7

3

2

9

4

2

2

12

12

6

1

2

4

Immune (3)

5

6

4

5

1

5

6

7

3

3

8

6

2

2

7

15

5

1

2

5

Non-Immune (41)

6

6

4

6

2

6

8

5

3

3

6

4

2

3

8

17

5

1

2

5

Immune (6)

6

6

3

5

2

4

7

6

2

2

8

4

2

2

15

14

5

1

2

4

Non-Immune (18)

7

6

3

4

1

5

6

7

3

2

9

4

2

2

12

12

6

1

2

4

Immune (9)

6

5

3

5

2

5

6

7

3

2

7

4

2

2

9

19

7

1

2

4

Non-Immune (23)

5

6

4

6

1

4

6

6

2

3

10

5

2

3

5

19

6

0

2

4

Immune (12)

7

5

3

5

1

6

13

6

3

2

9

4

2

1

15

7

4

0

2

6

Non-Immune (2)

8

6

2

5

1

4

9

7

2

2

8

6

2

2

15

10

5

1

2

4

Immune (15)

18

5

3

4

1

8

7

7

1

3

10

5

2

1

5

8

5

0

1

7

Non-Immune (126)

17

6

3

3

1

4

8

6

2

3

8

5

2

2

11

7

5

1

1

6

Immune (29)

7

6

4

6

1

5

11

6

2

3

8

8

3

2

6

9

5

1

2

5

Non-Immune (26)

5

6

4

6

1

5

9

5

2

4

9

8

2

3

7

10

6

1

2

4

Immune (36)

6

7

4

4

1

12

11

4

2

3

12

9

2

2

4

8

4

0

1

3

Non-Immune (30)

4

5

4

4

2

13

10

6

2

2

11

11

2

2

5

5

4

0

3

6

Immune (38)

7

4

3

4

2

4

6

7

2

1

9

4

2

3

20

10

4

1

2

5

Non-Immune (31)

6

4

3

6

1

5

4

6

3

2

9

3

2

2

20

12

6

1

1

4

Immune (41)

5

4

4

10

1

5

16

6

2

4

7

7

2

1

6

11

4

0

2

4

Non-Immune (38)

6

5

4

6

2

5

14

5

2

4

7

6

2

2

6

12

6

1

2

5

Immune (53)

5

6

4

4

2

5

10

7

2

3

5

4

2

2

8

11

7

1

2

8

Non-Immune (26)

5

6

4

6

1

5

9

5

2

4

9

8

2

3

7

10

6

1

2

4

Immune (56)

7

9

3

3

2

5

4

4

2

3

12

5

2

2

13

11

6

0

1

5

Non-Immune (18)

7

6

3

4

1

5

6

7

3

2

9

4

2

2

12

12

6

1

2

4

Immune (72)

8

9

4

4

1

5

7

5

3

3

6

4

2

2

7

12

10

1

1

4

Non-Immune (55)

8

11

3

4

1

4

9

6

3

2

8

5

2

2

7

13

5

1

2

4

Immune (79)

7

5

4

9

1

4

8

5

3

3

9

4

4

4

8

10

5

1

2

5

Non-Immune (26)

5

6

4

6

1

5

9

5

2

4

9

8

2

3

7

10

6

1

2

4

Immune (80)

11

6

1

4

0

9

10

5

1

3

4

13

2

2

15

7

5

1

1

3

Non-Immune (2)

8

6

2

5

1

4

9

7

2

2

8

6

2

2

15

10

5

1

2

4

Immune (94)

6

4

3

5

2

6

8

5

2

3

6

17

3

2

7

9

5

1

2

5

Non-Immune (42)

6

5

4

5

1

4

9

7

2

4

8

15

2

2

5

6

6

1

2

5

Immune (100)

4

6

3

7

2

13

14

6

2

3

6

5

2

1

9

7

6

0

1

5

Non-Immune (38)

6

5

4

6

2

5

14

5

2

4

7

6

2

2

6

12

6

1

2

5

Immune (107)

4

4

3

6

1

5

16

7

2

2

9

2

2

2

9

13

6

0

2

6

Non-Immune (38)

6

5

4

6

2

5

14

5

2

4

7

6

2

2

6

12

6

1

2

5

Immune (115)

6

4

3

5

1

4

9

6

2

4

6

11

2

2

11

10

7

1

1

4

Non-Immune (26)

5

6

4

6

1

5

9

5

2

4

9

8

2

3

7

10

6

1

2

4

Immune (175)

9

3

2

4

1

6

7

8

3

2

13

3

1

2

16

10

5

0

1

4

Non-Immune (2)

8

6

2

5

1

4

9

7

2

2

8

6

2

2

15

10

5

1

2

4

  1. The actual average histogram values for each cluster are shown as a percentage, in the order immune, non-immune cluster.
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